Group members

Group members

Current group members


Elin Larsson, PhD, Labmanager

Elin is a biochemist and cell biologist working on protein complexes that stabilise caveolae to the cell surface


Kang Liu, PhD, post doc

Kang is a protein biochemist and structural biologist working on the structure of the caveolae coat.


Hudson Pace, PhD, post doc

Hudson is a lipid biochemist and biophysisist working on characterisation of the components of the caveolae coat.


Agnieszka Pastula, PhD, post doc

Agnieszka is a cell biologist working on the role of endocytosis in preventing epithelial to mesencymal transition and metastasis.


Wai Lok Yau, PhD, post doc

Lok is a biochemist and cell biologist working on how viral proteins create replication compartment in cells.


Albin Jakobsson, Medical student appointed to the research aspirant program

Albin is a medical student working on the mechanisms of fatty acid internalisaition.

OUR EXCELLENT TEAM

Elin Larsson, PhD

Labmanager


Albin Jakobsson

Medical student and forskaraspirant


Kang Cheng Liu, PhD

Post doc


Richard Lundmark, PhD

Associate Professor


Hudson Pace, PhD

Post doc


Agnieszka Pastula, PhD

Post doc


Gallery

Previous group members

Björn Morén, PhD

Björn was the first PhD student in the lab and he defended his thesis in 2014: "Caveolae associated proteins and how they effect caveolae dynamics”


Doherty GJ, Åhlund MK, Howes M, Morén B, Parton RG, McMahon HT, Lundmark R; The endocytic protein GRAF1 is directed to cell matrix adhesion sites and regulates cell spreading. Molecular Biology of the Cell, 22, 4380-9 (2011).


Morén B, Shah C, Howes MT, Schieber NL, McMahon HT, Parton RG, Daumke O, Lundmark R; EHD2 regulates caveola dynamics via ATP-driven targeting and oligomerization. Molecular Biology of the Cell, 23, 1316-29 (2012).


Shah C, Hegde B, Morén B, Behrmann E, Mielke T, Moenke G, Spahn C, Richard Lundmark R, Daumke O, Ralf Langen R; Structural insights into membrane interaction and caveolar targeting of dynamin-like EHD2. Structure, 22, 409-20 (2014).


Mohan J, Morén B, Larsson E, Holst MR, Lundmark R; Cavin3 interacts with cavin1 and caveolin1 to increase surface dynamics of caveolae. Journal of Cell Science, 128, 979-91 (2015).


Morén B, Hansson B, Lundmark R, Göransson O, Stenkula KG; EHD2 regulates adipocyte function and is enriched at cell surface-associated lipid droplets in primary human adipocytes. Molecular Biology of the Cell, 30, 1147-59, doi: 10.1091/mbc.E18-10-0680 (2019).

Jagan Mohan, PhD

Jagan was a PhD student in the lab and he defended his thesis in 2016 “Regulation of assembly and cell surface dynamics of caveolae”


Mohan J, Morén B, Larsson E, Holst MR, Lundmark R; Cavin3 interacts with cavin1 and caveolin1 to increase surface dynamics of caveolae. Journal of Cell Science, 128, 979-91 (2015).


Hoernke M, Mohan J, Larsson E, Blomberg J, Kahra D, Westenhoff S, Schwieger C, Lundmark R; EHD2 restrains dynamics of caveolae by an ATP‑dependent, membrane-bound, open conformation Proceedings of the National Academy of Sciences, USA,114(22), E4360-E4369 (2017).


Madlen Hubert, PhD

Madlen was a post doc in the lab working on the role of lipids in regulating biogenesis and surface stability of caveolae.


Holst MR, Vidal-Quadras M, Larsson E, Song J, Hubert M, Blomberg J, Lundborg M, Landström M and Lundmark R; Clathrin-independent endocytosis suppresses cancer cell blebbing and invasion. Cell Reports, 20, 1893-1905, (2017).


Moodie LWK, Hubert M, Zhou X, Albers MF, Lundmark R, Wanrooij S and Christian Hedberg; Photoactivated Colibactin Probes Induce Cellular DNA Damage. Angewandte Chemie international edition, 58, 1417-22, doi: 10.1002/ange.201812326, (2019).


Rodrigues L, Schneider F, Zhang X, Larsson E, Moodie L, Dietz H, Papadakis CM, Gerhard Winter G, Lundmark R, Hubert M; Cellular uptake of self-assembled phytantriol-based hexosomes is independent of major endocytic machineries. Journal of Colloid and interphase science, 553, 820-833. doi: 10.1016/j.jcis.2019.06.045. (2019)


Hubert M, Larsson E and Lundmark R; Keeping in touch with the membrane; protein- and lipid-mediated confinement of caveolae to the cell surface. Biochemical Society Transactions. Accepted. invited peer-reviewed. (2020).     



Monica Åhlund, PhD

Monica was a PhD student in the lab and she defended her thesis in 2015: “Regulation of GRAF1 membrane sculpting function during cell movement”


Doherty GJ, Åhlund MK, Howes M, Morén B, Parton RG, McMahon HT, Lundmark R; The endocytic protein GRAF1 is directed to cell matrix adhesion sites and regulates cell spreading. Molecular Biology of the Cell, 22, 4380-9 (2011).


Francis MK, Holst MR, Vidal-Quadras M, Henriksson S, Sandblad L and Lundmark R; Endocytic membrane turnover at the leading edge is driven by a transient interaction between Cdc42 and GRAF1. Journal of Cell Science, 128, 4183-95 (2015).


Rompikuntal PK, Vdovikova S, Duperthuy M, Johnson TL, Monika Åhlund M, Lundmark R, Oscarsson J, Sandkvist M, Uhlin BE, Wai SN; Outer membrane vesicle-mediated export of processed PrtV protease from Vibrio cholera; PLOS one, 10(7) (2015).


Vidal-Quadras M, Holst M, R, Francis M, K, Larssson E, Hachimi M, Yau W, L, Peränen J, Martín-Belmonte F and Lundmark R; Endocytic turnover of Rab8 controls cell polarization; Journal of Cell Science, 130, 1147-1157. (2017).


Vdovikova S, Luhr M, Szalai P, Nygård Skalman L, Francis MK, Lundmark R, Engedal N, Johansson J, Nyunt Wai S; A novel role of Listeria monocytogenes membrane vesicles in inhibition of autophagy and cell death. Frontiers in Cellular and Infection Microbiology, 7:154. (2017).

Lars Nygård-Skalman, PhD

Lars was a PhD student in the lab and she defended his thesis in 2017:  “Pathogen entry mechanisms and endocytic responses to plasma membrane damage”


Olofsson A1, Nygård Skalman L1, Ikenna O, Lundmark R, and Arnqvist A; Uptake of Helicobacter pylori vesicles is facilitated by clathrin-dependent and clathrin-independent endocytic pathways; mBio, 5, e00979-14 (2014) 1 These authors contributed equally to this work.


Storm RJ, Persson BD, Nygård Skalman L, Frängsmyr L, Lindström M, Rankin G, Lundmark R, Pedrosa Domellöf F, Arnberg N; Human adenovirus type 37 uses αVβ1 and α3β1 integrins for infection of human corneal cells. Journal of Virology, 91(5) (2017).


Vdovikova S, Luhr M, Szalai P, Nygård Skalman L, Francis MK, Lundmark R, Engedal N, Johansson J, Nyunt Wai S; A novel role of Listeria monocytogenes membrane vesicles in inhibition of autophagy and cell death. Frontiers in Cellular and Infection Microbiology, 7:154. (2017).


Vonderstein K, Nilsson E, Hubel P, Nygård Skalman L, Upadhyay A, Pasto J, Andreas Pichlmair A, Lundmark R, and Överby A; Viperin targets flavivirus virulence by inducing assembly of non-infectious capsid particles. Journal of Virology, 92. JVI.01751-17. (2017).


Nygard-Skalman L, Holst MR, Larsson E, Lundmark R; Plasma membrane damage caused by Listeriolysin O is not repaired through endocytosis of the membrane pore. Biology Open, 7, doi: 10.1242/bio.03528, (2018).

Mikkel Roland Holst, PhD

Mikkel was a post doc in the lab working on the protein GRAF1 and its role in generating an endocytic membrane reservoir in response to altered membrane tension.


Mohan J, Morén B, Larsson E, Holst MR, Lundmark R; Cavin3 interacts with cavin1 and caveolin1 to increase surface dynamics of caveolae. Journal of Cell Science, 128, 979-91 (2015).


Francis MK, Holst MR, Vidal-Quadras M, Henriksson S, Sandblad L and Lundmark R; Endocytic membrane turnover at the leading edge is driven by a transient interaction between Cdc42 and GRAF1. Journal of Cell Science, 128, 4183-95 (2015).


Vidal-Quadras M, Holst M, R, Francis M, K, Larssson E, Hachimi M, Yau W, L, Peränen J, Martín-Belmonte F and Lundmark R; Endocytic turnover of Rab8 controls cell polarization; Journal of Cell Science, 130, 1147-1157. (2017).


Holst MR, Vidal-Quadras M, Larsson E, Song J, Hubert M, Blomberg J, Lundborg M, Landström M and Lundmark R; Clathrin-independent endocytosis suppresses cancer cell blebbing and invasion. Cell Reports, 20, 1893-1905, (2017).


Daste F*, Walrant A*, Holst MR*, Gadsby JR*, Mason J, Lee, J, Brook D, Mettlen M, Larsson E, Lee SF, Lundmark R and Gallop JL; Control of actin polymerization via the coincidence of phosphoinositides and high membrane curvature. Journal of Cell Biology, 216, 3745-3765, (2017). * These authors contributed equally to this work.

Ngyuen din Van, PhDK

Ken was a post doc in the lab working on the biogenesis of TBEV replication compartments


Yau WL, Nguyen-Dinh V, Larsson E, Lindqvist R, Överby AK, Lundmark R; Model System for the Formation of Tick-Borne Encephalitis Virus Replication Compartments without Viral RNA Replication. Journal of Virology, Jun 26, JVI.00292-19. doi: 10.1128/JVI.00292-19, (2019)

Wai Lok, PhDK

Lok was a post doc in the lab working on TBEV replication compartments


Yau WL, Nguyen-Dinh V, Larsson E, Lindqvist R, Överby AK, Lundmark R; Model System for the Formation of Tick-Borne Encephalitis Virus Replication Compartments without Viral RNA Replication. Journal of Virology, Jun 26, JVI.00292-19. doi: 10.1128/JVI.00292-19, (2019)


Vidal-Quadras M, Holst M, R, Francis M, K, Larssson E, Hachimi M, Yau W, L, Peränen J, Martín-Belmonte F and Lundmark R; Endocytic turnover of Rab8 controls cell polarization; Journal of Cell Science, 130, 1147-1157. (2017).

Maria Vidal-Quadras, PhD

Maite was a post doc in the lab working on the coupling between endo- and exocytosis and its impact on cell polarity


Francis MK, Holst MR, Vidal-Quadras M, Henriksson S, Sandblad L and Lundmark R; Endocytic membrane turnover at the leading edge is driven by a transient interaction between Cdc42 and GRAF1. Journal of Cell Science, 128, 4183-95 (2015).


Vidal-Quadras M, Holst M, R, Francis M, K, Larssson E, Hachimi M, Yau W, L, Peränen J, Martín-Belmonte F and Lundmark R; Endocytic turnover of Rab8 controls cell polarization; Journal of Cell Science, 130, 1147-1157. (2017).


Holst MR, Vidal-Quadras M, Larsson E, Song J, Hubert M, Blomberg J, Lundborg M, Landström M and Lundmark R; Clathrin-independent endocytosis suppresses cancer cell blebbing and invasion. Cell Reports, 20, 1893-1905, (2017).

Sara Henriksson, PhD

Sara was a shared post doc in the lab working on correlative imaging techniques together with the Biochemical Imaging Centre


Francis MK, Holst MR, Vidal-Quadras M, Henriksson S, Sandblad L and Lundmark R; Endocytic membrane turnover at the leading edge is driven by a transient interaction between Cdc42 and GRAF1. Journal of Cell Science, 128, 4183-95 (2015).